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Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with few effective therapeutic options. Structural remodelling of the extracellular matrix [i.e. collagen cross-linking mediated by the lysyl oxidase (LO) family of enzymes (LOX, LOXL1-4)] might contribute to disease p...
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Main Authors: | , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
The Company of Biologists
2017-11-01
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叢編: | Disease Models & Mechanisms |
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在線閱讀: | http://dmm.biologists.org/content/10/11/1301 |
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