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Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach
We present an integrated study to understand the key role of senescent fibroblasts in driving melanoma progression. Based on the hybrid cellular automata paradigm we developed an in silico model of normal skin. The model focuses on key cellular and microenvironmental variables that regulate interact...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926439/ https://ncbi.nlm.nih.gov/pubmed/24080279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1720 |
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