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Phase i trials in melanoma: A framework to translate preclinical findings to the clinic

BACKGROUND: One of major issues in clinical trials in oncology is their high failure rate, despite the fact that the trials were designed based on the data from successful equivalent preclinical studies. This is in part due to the intrinsic homogeneity of preclinical model systems and the contrastin...

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Detalhes bibliográficos
Publicado no:Eur J Cancer
Main Authors: Kim, Eunjung, Rebecca, Vito W., Smalley, Keiran S.M., Anderson, Alexander R.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658204/
https://ncbi.nlm.nih.gov/pubmed/27689717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2016.07.024
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