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Phase i trials in melanoma: A framework to translate preclinical findings to the clinic
BACKGROUND: One of major issues in clinical trials in oncology is their high failure rate, despite the fact that the trials were designed based on the data from successful equivalent preclinical studies. This is in part due to the intrinsic homogeneity of preclinical model systems and the contrastin...
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| Publicado en: | Eur J Cancer |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658204/ https://ncbi.nlm.nih.gov/pubmed/27689717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2016.07.024 |
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