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Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach

We present an integrated study to understand the key role of senescent fibroblasts in driving melanoma progression. Based on the hybrid cellular automata paradigm we developed an in silico model of normal skin. The model focuses on key cellular and microenvironmental variables that regulate interact...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Eunjung, Rebecca, Vito, Fedorenko, Inna V., Messina, Jane L., Mathew, Rahel, Maria-Engler, Silvya S., Basanta, David, Smalley, Keiran S.M., Anderson, Alexander R.A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926439/
https://ncbi.nlm.nih.gov/pubmed/24080279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1720
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