Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

Antiretroviral therapy can reduce HIV-1 to undetectable levels in peripheral blood, but the effectiveness of treatment in suppressing replication in lymphoid tissue reservoirs has not been determined. Here we show in lymph node samples obtained before and during 6 mo of treatment that the tissue con...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fletcher, Courtney V., Staskus, Kathryn, Wietgrefe, Stephen W., Rothenberger, Meghan, Reilly, Cavan, Chipman, Jeffrey G., Beilman, Greg J., Khoruts, Alexander, Thorkelson, Ann, Schmidt, Thomas E., Anderson, Jodi, Perkey, Katherine, Stevenson, Mario, Perelson, Alan S., Douek, Daniel C., Haase, Ashley T., Schacker, Timothy W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2014
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926074/
https://ncbi.nlm.nih.gov/pubmed/24469825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318249111
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