RNA design rules from a massive open laboratory

Self-assembling RNA molecules present compelling substrates for the rational interrogation and control of living systems. However, imperfect in silico models—even at the secondary structure level—hinder the design of new RNAs that function properly when synthesized. Here, we present a unique and pot...

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Autori principali: Lee, Jeehyung, Kladwang, Wipapat, Lee, Minjae, Cantu, Daniel, Azizyan, Martin, Kim, Hanjoo, Limpaecher, Alex, Gaikwad, Snehal, Yoon, Sungroh, Treuille, Adrien, Das, Rhiju
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926058/
https://ncbi.nlm.nih.gov/pubmed/24469816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313039111
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