JAK2V(617)F-positive endothelial cells contribute to clotting abnormalities in myeloproliferative neoplasms

The Janus kinase 2 (JAK2) V(617)F mutation is the primary pathogenic mutation in patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs). Although thrombohemorrhagic incidents are the most common causes of morbidity and mortality in patients with MPNs, the events causing t...

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Detalhes bibliográficos
Principais autores: Etheridge, S. Leah, Roh, Michelle E., Cosgrove, Megan E., Sangkhae, Veena, Fox, Norma E., Chen, Junmei, López, José A., Kaushansky, Kenneth, Hitchcock, Ian S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926040/
https://ncbi.nlm.nih.gov/pubmed/24469804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312148111
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