Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer

Using complete genome analysis, we sequenced five bladder tumors accrued from patients with muscle-invasive transitional cell carcinoma of the urinary bladder (TCC-UB) and identified a spectrum of genomic aberrations. In three tumors, complex genotype changes were noted. All three had tumor protein...

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Detalhes bibliográficos
Principais autores: Morrison, Carl D., Liu, Pengyuan, Woloszynska-Read, Anna, Zhang, Jianmin, Luo, Wei, Qin, Maochun, Bshara, Wiam, Conroy, Jeffrey M., Sabatini, Linda, Vedell, Peter, Xiong, Donghai, Liu, Song, Wang, Jianmin, Shen, He, Li, Yinwei, Omilian, Angela R., Hill, Annette, Head, Karen, Guru, Khurshid, Kunnev, Dimiter, Leach, Robert, Eng, Kevin H., Darlak, Christopher, Hoeflich, Christopher, Veeranki, Srividya, Glenn, Sean, You, Ming, Pruitt, Steven C., Johnson, Candace S., Trump, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926024/
https://ncbi.nlm.nih.gov/pubmed/24469795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313580111
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