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Brd4 and HEXIM1: Multiple Roles in P-TEFb Regulation and Cancer
Bromodomain-containing protein 4 (Brd4) and hexamethylene bisacetamide (HMBA) inducible protein 1 (HEXIM1) are two opposing regulators of the positive transcription elongation factor b (P-TEFb), which is the master modulator of RNA polymerase II during transcriptional elongation. While Brd4 recruits...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Hindawi Publishing Corporation
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925632/ https://ncbi.nlm.nih.gov/pubmed/24592384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/232870 |
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