BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene

We previously reported that induction of the adipocyte-specific gene adiponectin (Adipoq) during 3T3-L1 adipocyte differentiation is closely associated with epigenetic memory histone H3 acetylation on the transcribed region of the gene. We used 3T3-L1 adipocytes and Brd4 heterozygous mice to investi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakurai, Naoko, Inamochi, Yuko, Inoue, Takuya, Hariya, Natsuyo, Kawamura, Musashi, Yamada, Masami, Dey, Anup, Nishiyama, Akira, Kubota, Takeo, Ozato, Keiko, Goda, Toshinao, Mochizuki, Kazuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607256/
https://ncbi.nlm.nih.gov/pubmed/28931940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12342-2
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