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Apolipoprotein CIII hyperactivates β cell Ca(V)1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src
Apolipoprotein CIII (ApoCIII) not only serves as an inhibitor of triglyceride hydrolysis but also participates in diabetes-related pathological events such as hyperactivation of voltage-gated Ca(2+) (Ca(V)) channels in the pancreatic β cell. However, nothing is known about the molecular mechanisms w...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Basel
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925466/ https://ncbi.nlm.nih.gov/pubmed/23949443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1442-x |
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