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Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper formation...

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Detalhes bibliográficos
Main Authors: Li, Ying, Hao, Hailing, Tzatzalos, Evangeline, Lin, Ren-Kuo, Doh, Sungtae, Liu, Leroy F., Lyu, Yi Lisa, Cai, Li
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925320/
https://ncbi.nlm.nih.gov/pubmed/24463367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20146767
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