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Genistein Induces Topoisomerasae IIbeta- and Proteasome-Mediated DNA Sequence Rearrangements: Implications in Infant Leukemia

Genistein is a bioflavonoid enriched in soy products. However, high levels of maternal soy consumption have been linked to the development of infant leukemia ALL and AML. The majority of infant leukemia is linked to mixed lineage leukemia gene (MLL) translocations. Previous studies have implicated t...

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Detalhes bibliográficos
Main Authors: Azarova, Anna M., Lin, Ren-Kuo, Tsai, Yuan-Chin, Liu, Leroy F., Lin, Chao-Po, Lyu, Yi Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376163/
https://ncbi.nlm.nih.gov/pubmed/20638367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.043
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