Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper formation...

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Dettagli Bibliografici
Autori principali: Li, Ying, Hao, Hailing, Tzatzalos, Evangeline, Lin, Ren-Kuo, Doh, Sungtae, Liu, Leroy F., Lyu, Yi Lisa, Cai, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925320/
https://ncbi.nlm.nih.gov/pubmed/24463367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20146767
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