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Diverse functions of PHD fingers of the MLL/KMT2 subfamily

Five members of the KMT2 family of lysine methyltransferases, originally named the mixed lineage leukemia (MLL1-5) proteins, regulate gene expression during embryogenesis and development. Each KMT2A-E contains a catalytic SET domain that methylates lysine 4 of histone H3, and one or several PHD fing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ali, Muzaffar, Hom, Robert A., Blakeslee, Weston, Ikenouye, Larissa, Kutateladze, Tatiana G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925188/
https://ncbi.nlm.nih.gov/pubmed/24291127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.11.016
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