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Multiple Tumor Suppressor microRNAs Regulate Telomerase and TCF7, an Important Transcriptional Regulator of the Wnt Pathway

The human TERT (hTERT) gene encodes the telomerase catalytic subunit which plays a role in telomerase regulation. Telomerase is activated in more than 90% of all human malignancies and understanding how telomerase is regulated is necessary for implementation of successful anti-cancer therapies. micr...

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Detalles Bibliográficos
Main Authors: Hrdličková, Radmila, Nehyba, Jiří, Bargmann, William, Bose, Henry R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925088/
https://ncbi.nlm.nih.gov/pubmed/24551047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086990
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