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Dynamic Evolution of Immune System Regulators: The History of the Interferon Regulatory Factor Family

This manuscript presents the first extensive phylogenetics analysis of a key family of immune regulators, the interferon regulatory factor (IRF) family. The IRF family encodes transcription factors that play important roles in immune defense, stress responses, reproduction, development, and carcinog...

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Detalhes bibliográficos
Main Authors: Nehyba, Jiří, Hrdličková, Radmila, Bose, Henry R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767096/
https://ncbi.nlm.nih.gov/pubmed/19638535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp167
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