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Mechanism of Telomerase Activation by v-Rel and Its Contribution to Transformation

Telomerase is activated during the transformation of lymphoid cells and fibroblasts by v-Rel, the oncogenic member of the Rel/NF-κB family of transcription factors. v-Rel-transformed cell lines have longer telomeres than untransformed chicken lymphoid cells and have high levels of telomerase activit...

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Autori principali: Hrdličková, Radmila, Nehyba, Jiří, Liss, Andrew S., Bose, Henry R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317554/
https://ncbi.nlm.nih.gov/pubmed/16352553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.281-295.2006
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