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Mutational Analysis of the v-Rel Dimerization Interface Reveals a Critical Role for v-Rel Homodimers in Transformation

The v-rel oncogene encoded by reticuloendotheliosis virus strain T is the acutely transforming member of the Rel/NF-κB family of transcription factors. In v-Rel-transformed cells, v-Rel exists as homodimers or heterodimers with the endogenous Rel/NF-κB proteins c-Rel, NF-κB1, NF-κB2, and RelA. To ex...

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Bibliografiske detaljer
Main Authors: Liss, Andrew S., Bose, Jr., Henry R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136140/
https://ncbi.nlm.nih.gov/pubmed/11967310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.4928-4939.2002
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