Kaposi's Sarcoma-Associated Herpesvirus-Induced Upregulation of the c-kit Proto-Oncogene, as Identified by Gene Expression Profiling, Is Essential for the Transformation of Endothelial Cells

Kaposi's sarcoma (KS), the most frequent malignancy afflicting AIDS patients, is characterized by spindle cell formation and vascularization. Infection with KS-associated herpesvirus (KSHV) is consistently observed in all forms of KS. Spindle cell formation can be replicated in vitro by infecti...

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Main Authors: Moses, Ashlee V., Jarvis, Michael A., Raggo, Camilo, Bell, Yolanda C., Ruhl, Rebecca, Luukkonen, B. G. Mattias, Griffith, Diana J., Wait, Cecily L., Druker, Brian J., Heinrich, Michael C., Nelson, Jay A., Früh, Klaus
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Transformation and Oncogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC155158/
https://ncbi.nlm.nih.gov/pubmed/12134042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.16.8383-8399.2002
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