Kaposi's Sarcoma-Associated Herpesvirus-Induced Upregulation of the c-kit Proto-Oncogene, as Identified by Gene Expression Profiling, Is Essential for the Transformation of Endothelial Cells

Kaposi's sarcoma (KS), the most frequent malignancy afflicting AIDS patients, is characterized by spindle cell formation and vascularization. Infection with KS-associated herpesvirus (KSHV) is consistently observed in all forms of KS. Spindle cell formation can be replicated in vitro by infection of...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Moses, Ashlee V., Jarvis, Michael A., Raggo, Camilo, Bell, Yolanda C., Ruhl, Rebecca, Luukkonen, B. G. Mattias, Griffith, Diana J., Wait, Cecily L., Druker, Brian J., Heinrich, Michael C., Nelson, Jay A., Früh, Klaus
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Transformation and Oncogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12134042/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.16.8383-8399.2002
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