Mutational Analysis of the v-Rel Dimerization Interface Reveals a Critical Role for v-Rel Homodimers in Transformation

The v-rel oncogene encoded by reticuloendotheliosis virus strain T is the acutely transforming member of the Rel/NF-κB family of transcription factors. In v-Rel-transformed cells, v-Rel exists as homodimers or heterodimers with the endogenous Rel/NF-κB proteins c-Rel, NF-κB1, NF-κB2, and RelA. To ex...

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Pubblicato in:	J Virol
Autori principali:	Liss, Andrew S., Bose, Jr., Henry R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Transformation and Oncogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11967310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.10.4928-4939.2002
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