Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket

Lignende værker

• Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-targeting Pyruvate Dehydrogenase Kinase Inhibitors
  af: Tso, Shih-Chia, et al.
  Udgivet: (2017)
• Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex
  af: Kato, Masato, et al.
  Udgivet: (2005)
• Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase
  af: Tso, Shih-Chia, et al.
  Udgivet: (2013)
• Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase
  af: Tso, Shih-Chia, et al.
  Udgivet: (2014)
• Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice
  af: Wu, Cheng-Yang, et al.
  Udgivet: (2018)