Single Molecule Analysis Reveals Coexistence of Stable Serotonin Transporter Monomers and Oligomers in the Live Cell Plasma Membrane

The human serotonin transporter (hSERT) is responsible for the termination of synaptic serotonergic signaling. Although there is solid evidence that SERT forms oligomeric complexes, the exact stoichiometry of the complexes and the fractions of different coexisting oligomeric states still remain enig...

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Autors principals: Anderluh, Andreas, Klotzsch, Enrico, Reismann, Alexander W. A. F., Brameshuber, Mario, Kudlacek, Oliver, Newman, Amy Hauck, Sitte, Harald H., Schütz, Gerhard J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924301/
https://ncbi.nlm.nih.gov/pubmed/24394416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531632
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