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Improved Ligand Discrimination by Force-Induced Unbinding of the T Cell Receptor from Peptide-MHC
T cell activation is mediated via the recognition of peptides by the T cell receptor (TCR). This receptor ligand interaction is highly specific, and the TCR has to discriminate between a huge number of peptides presented by the products of the major histocompatibility complexes (MHCs). Recent studie...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628311/ https://ncbi.nlm.nih.gov/pubmed/23601314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.023 |
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