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Direct PIP(2) binding mediates stable oligomer formation of the serotonin transporter

The human serotonin transporter (hSERT) mediates uptake of serotonin from the synaptic cleft and thereby terminates serotonergic signalling. We have previously found by single-molecule microscopy that SERT forms stable higher-order oligomers of differing stoichiometry at the plasma membrane of livin...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Anderluh, Andreas, Hofmaier, Tina, Klotzsch, Enrico, Kudlacek, Oliver, Stockner, Thomas, Sitte, Harald H., Schütz, Gerhard J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253637/
https://ncbi.nlm.nih.gov/pubmed/28102201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14089
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