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Direct PIP(2) binding mediates stable oligomer formation of the serotonin transporter

The human serotonin transporter (hSERT) mediates uptake of serotonin from the synaptic cleft and thereby terminates serotonergic signalling. We have previously found by single-molecule microscopy that SERT forms stable higher-order oligomers of differing stoichiometry at the plasma membrane of livin...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Anderluh, Andreas, Hofmaier, Tina, Klotzsch, Enrico, Kudlacek, Oliver, Stockner, Thomas, Sitte, Harald H., Schütz, Gerhard J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253637/
https://ncbi.nlm.nih.gov/pubmed/28102201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14089
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