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Changes of protein stiffness during folding detect protein folding intermediates

Single-molecule force-quench atomic force microscopy (FQ-AFM) is used to detect folding intermediates of a simple protein by detecting changes of molecular stiffness of the protein during its folding process. Those stiffness changes are obtained from shape and peaks of an autocorrelation of fluctuat...

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Detalhes bibliográficos
Main Authors: Małek, Katarzyna E., Szoszkiewicz, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923959/
https://ncbi.nlm.nih.gov/pubmed/23975672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-013-9331-y
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