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Changes of protein stiffness during folding detect protein folding intermediates

Single-molecule force-quench atomic force microscopy (FQ-AFM) is used to detect folding intermediates of a simple protein by detecting changes of molecular stiffness of the protein during its folding process. Those stiffness changes are obtained from shape and peaks of an autocorrelation of fluctuat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Małek, Katarzyna E., Szoszkiewicz, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923959/
https://ncbi.nlm.nih.gov/pubmed/23975672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-013-9331-y
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