WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma

Developmental and cancer models show Wnt/β-catenin-dependent signaling mediates diverse phenotypic outcomes in the pancreas that are dictated by context, duration and strength of activation. While generally assumed to be pro-tumorigenic, it is unclear to what extent dysregulation of Wnt/β-catenin si...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Arensman, Michael D., Kovochich, Anne N., Kulikauskas, Rima M., Lay, Anna R., Yang, Pei-Tzu, Li, Xinmin, Donahue, Timothy, Major, Michael B., Moon, Randall T., Chien, Andy J., Dawson, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923845/
https://ncbi.nlm.nih.gov/pubmed/23416978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.23
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky