Matriptase Deletion Initiates a Sjögren’s Syndrome-Like Disease in Mice

OBJECTIVE: The objective of this study was to determine the effect of epithelial barrier disruption, caused by deficiency of the membrane-anchored serine protease, matriptase, on salivary gland function and the induction of autoimmunity in an animal model. METHODS: Embryonic and acute ablation of ma...

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Detalhes bibliográficos
Main Authors: Yin, Hongen, Kosa, Peter, Liu, Xibao, Swaim, William D., Lai, Zhennan, Cabrera-Perez, Javier, Di Pasquale, Giovanni, Ambudkar, Indu S., Bugge, Thomas H., Chiorini, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923742/
https://ncbi.nlm.nih.gov/pubmed/24551030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082852
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