Aquaporin gene therapy corrects Sjögren’s syndrome phenotype in mice

Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease that is estimated to affect 35 million people worldwide. Currently, no effective treatments exist for Sjögren’s syndrome, and there is a limited understanding of the physiological mechanisms associated with xerostomia and hyposalivatio...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lai, Zhennan, Yin, Hongen, Cabrera-Pérez, Javier, Guimaro, Maria C., Afione, Sandra, Michael, Drew G., Glenton, Patricia, Patel, Ankur, Swaim, William D., Zheng, Changyu, Nguyen, Cuong Q., Nyberg, Fred, Chiorini, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878512/
https://ncbi.nlm.nih.gov/pubmed/27140635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601992113
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