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STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjögren's syndrome

Primary Sjögren's Syndrome (pSS) is an autoimmune disease involving salivary and other exocrine glands that leads to progressive lymphocytic infiltration into the gland, tissue damage, and secretory defects. The mechanism underlying this disease remains poorly understood. Here we report that mi...

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Detalhes bibliográficos
Main Authors: Cheng, Kwong Tai, Alevizos, Ilias, Liu, Xibao, Swaim, Wiliam D., Yin, Hongen, Feske, Stefan, Oh-hora, Masatsugu, Ambudkar, Indu S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437853/
https://ncbi.nlm.nih.gov/pubmed/22904194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207354109
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