Ikaros promotes rearrangement of TCR alpha genes in an Ikaros null thymoma cell line

Ikaros is important in the development and maintenance of the lymphoid system, functioning in part by associating with chromatin-remodeling complexes. We have studied the functions of Ikaros in the transition from pre-T cell to the CD4(+)CD8(+) thymocyte using an Ikaros null CD4(−)CD8(−) mouse thymo...

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Bibliographic Details
Main Authors: Collins, Bernard, Clambey, Eric T., Scott-Browne, James, White, Janice, Marrack, Philippa, Hagman, James, Kappler, John W.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923402/
https://ncbi.nlm.nih.gov/pubmed/23172374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242757
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