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Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties
CD8 memory T cells are tightly regulated in young, healthy individuals but are often perturbed in aged animals by the appearance of large CD8 T cell clones. These clones are associated with impaired immunity in the aged. The molecular basis of this phenomenon remains unclear. Here, it is shown that...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525558/ https://ncbi.nlm.nih.gov/pubmed/18728183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805465105 |
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