Llwytho...

Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties

CD8 memory T cells are tightly regulated in young, healthy individuals but are often perturbed in aged animals by the appearance of large CD8 T cell clones. These clones are associated with impaired immunity in the aged. The molecular basis of this phenomenon remains unclear. Here, it is shown that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Clambey, Eric T., White, Janice, Kappler, John W., Marrack, Philippa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525558/
https://ncbi.nlm.nih.gov/pubmed/18728183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805465105
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!