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CD8 T Cell Clonal Expansions & Aging: A Heterogeneous Phenomenon with a Common Outcome
A highly diverse CD8 T cell repertoire is thought to be critical for maintaining appropriate immune defenses against a variety of pathogens. However, in many aged individuals, the diversity of T cell receptors is significantly reduced by the presence of large, monoclonal expansions of CD8 memory T c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905459/ https://ncbi.nlm.nih.gov/pubmed/17197145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.11.008 |
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