Stoichiometry of GTP hydrolysis and tubulin polymerization.

Microtubule formation from lamb brain tubulin isolated by affinity chromatography and freed of exchangeable nucleotide requires GTP for maximal rate and extent of polymerization. The nucleotide analogs guanylylmethylenediphosphate and guanylylimidodiphosphate fail to replace GTP; in addition, neithe...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Maccioni, R, Seeds, N W
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1977
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/191810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.2.462
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