Stoichiometry of GTP hydrolysis and tubulin polymerization.

Microtubule formation from lamb brain tubulin isolated by affinity chromatography and freed of exchangeable nucleotide requires GTP for maximal rate and extent of polymerization. The nucleotide analogs guanylylmethylenediphosphate and guanylylimidodiphosphate fail to replace GTP; in addition, neithe...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Maccioni, R, Seeds, N W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1977
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/191810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.2.462
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!