MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case–control samples

AIM: We studied the use of methyl-CpG binding domain (MBD) protein-enriched genome sequencing (MBD-seq) as a cost-effective screening tool for methylome-wide association studies (MWAS). MATERIALS & METHODS: Because MBD-seq has not yet been applied on a large scale, we first developed and tested...

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Auteurs principaux: Aberg, Karolina A, McClay, Joseph L, Nerella, Srilaxmi, Xie, Lin Y, Clark, Shaunna L, Hudson, Alexandra D, Bukszár, Jozsef, Adkins, Daniel, Consortium, Swedish Schizophrenia, Hultman, Christina M, Sullivan, Patrick F, Magnusson, Patrik KE, van den Oord, Edwin JCG
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923085/
https://ncbi.nlm.nih.gov/pubmed/23244307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.12.59
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