MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case–control samples

AIM: We studied the use of methyl-CpG binding domain (MBD) protein-enriched genome sequencing (MBD-seq) as a cost-effective screening tool for methylome-wide association studies (MWAS). MATERIALS & METHODS: Because MBD-seq has not yet been applied on a large scale, we first developed and tested...

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Detalhes bibliográficos
Main Authors: Aberg, Karolina A, McClay, Joseph L, Nerella, Srilaxmi, Xie, Lin Y, Clark, Shaunna L, Hudson, Alexandra D, Bukszár, Jozsef, Adkins, Daniel, Consortium, Swedish Schizophrenia, Hultman, Christina M, Sullivan, Patrick F, Magnusson, Patrik KE, van den Oord, Edwin JCG
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923085/
https://ncbi.nlm.nih.gov/pubmed/23244307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.12.59
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