Estimation of CpG coverage in whole methylome next-generation sequencing studies

BACKGROUND: Methylation studies are a promising complement to genetic studies of DNA sequence. However, detailed prior biological knowledge is typically lacking, so methylome-wide association studies (MWAS) will be critical to detect disease relevant sites. A cost-effective approach involves the nex...

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Hlavní autoři: van den Oord, Edwin JCG, Bukszar, Jozsef, Rudolf, Gábor, Nerella, Srilaxmi, McClay, Joseph L, Xie, Lin Y, Aberg, Karolina A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599116/
https://ncbi.nlm.nih.gov/pubmed/23398781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-50
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