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Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines

DNA from Epstein–Barr virus-transformed lymphocyte cell lines (LCLs) has proven useful for studies of genetic sequence polymorphisms. Whether LCL DNA is suitable for methylation studies is less clear. We conduct a genome-wide methylation investigation using an array set with 45 million probes to inv...

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Detalhes bibliográficos
Main Authors: Åberg, Karolina, Khachane, Amit N, Rudolf, Gábor, Nerella, Srilaxmi, Fugman, Douglas A, Tischfield, Jay A, van den Oord, Edwin JCG
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421118/
https://ncbi.nlm.nih.gov/pubmed/22378283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.33
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