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Impact of Bulge Loop Size on DNA Triplet Repeat Domains: Implications for DNA Repair and Expansion
Repetitive DNA sequences exhibit complex structural and energy landscapes, populated by metastable, non-canonical states, that favor expansion and deletion events correlated with disease phenotypes. To probe the origins of such genotype-phenotype linkages, we report the impact of sequence and repeat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920904/ https://ncbi.nlm.nih.gov/pubmed/23494673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22236 |
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