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Complex between α-bungarotoxin and an α7 nicotinic receptor ligand-binding domain chimaera

To identify high-affinity interactions between long-chain α-neurotoxins and nicotinic receptors, we determined the crystal structure of the complex between α-btx (α-bungarotoxin) and a pentameric ligand-binding domain constructed from the human α7 AChR (acetylcholine receptor) and AChBP (acetylcholi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Sun, Li, Shu-Xing, Bren, Nina, Cheng, Kevin, Gomoto, Ryan, Chen, Lin, Sine, Steven M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920732/
https://ncbi.nlm.nih.gov/pubmed/23800261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130636
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