The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification

Numerous studies indicate that γδ T cell receptor (γδTCR) expression alone does not reliably mark commitment of early thymic progenitors to the γδ fate. This raises the possibility that the γδTCR is unable to intrinsically specify fate and instead requires additional environmental factors, including...

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Main Authors: Coffey, Francis, Lee, Sang-Yun, Buus, Terkild B., Lauritsen, Jens-Peter Holst, Wong, Gladys W., Joachims, Michelle L., Thompson, Linda F., Zúñiga-Pflücker, Juan Carlos, Kappes, Dietmar J., Wiest, David L.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920555/
https://ncbi.nlm.nih.gov/pubmed/24493796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131540
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