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Differential induction of Id3 signals lineage divergence, Notch-independent differentiation, and functional maturation of γδ T cells
αβ and γδ T-cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR) and γδ T-cell receptor (γδTCR) play instructional roles in specifying the αβ and γδ T-lineage fates, respectively. Nevertheless, the signalin...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768560/ https://ncbi.nlm.nih.gov/pubmed/19833086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.07.010 |
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