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Enforcement of γδ-lineage commitment by the pre–T-cell receptor in precursors with weak γδ-TCR signals
Developing thymocytes bifurcate from a bipotent precursor into αβ- or γδ-lineage T cells. Considering this common origin and the fact that the T-cell receptor (TCR) β-, γ-, and δ-chains simultaneously rearrange at the double negative (DN) stage of development, the possibility exists that a given DN...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992653/ https://ncbi.nlm.nih.gov/pubmed/24706811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312872111 |
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