Role of a selecting ligand in shaping the murine γδ-TCR repertoire

Unlike αβ-T lineage cells, where the role of ligand in intrathymic selection is well established, the role of ligand in the development of γδ-T cells remains controversial. Here we provide evidence for the role of a bona fide selecting ligand in shaping the γδ-T cell-receptor (TCR) repertoire. React...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Fahl, Shawn P., Coffey, Francis, Kain, Lisa, Zarin, Payam, Dunbrack, Roland L., Teyton, Luc, Zúñiga-Pflücker, Juan Carlos, Kappes, Dietmar J., Wiest, David L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828614/
https://ncbi.nlm.nih.gov/pubmed/29432160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718328115
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