The p66(Shc) adapter protein regulates the morphogenesis and epithelial maturation of fetal mouse lungs

Many signaling pathways are mediated by Shc adapter proteins that, in turn, are expressed as three isoforms with distinct functions. The p66(Shc) isoform antagonizes proliferation, regulates oxidative stress, and mediates apoptosis. It is highly expressed in the canalicular but not the later stages...

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Главные авторы: Lee, M. K., Smith, S. M., Banerjee, Maalika M., Li, Changgong, Minoo, Parviz, Volpe, M. V., Nielsen, H. C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920229/
https://ncbi.nlm.nih.gov/pubmed/24375794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2013
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